2. Signaling Pathways
  3. ATP-binding Cassette (ABC) transporter

ATP-binding Cassette (ABC) transporter

ATP-binding Cassette (ABC) transporter

 

ATP-binding Cassette (ABC) transporter Related Products (2):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-101453
    Ceefourin 1
    		99.72%
    Ceefourin 1 is a potent and highly selective multidrug resistance protein 4 (MRP4) inhibitor. Ceefourin 1 inhibits transport of a broad range of MRP4 substrates, yet is highly selective for MRP4 over other ABC transporters. Ceefourin 1 is a benzothiazol and primarily as a chemosensitizer for high-risk neuroblastoma.
    Ceefourin 1
  • HY-P10856
    CPI1
    		Inhibitor
    CPI1 is a potent and highly specific multidrug resistance protein 1 (MRP1) inhibitor. CPI1 inhibits MRP1 (Ki: 100 nM) with nanomolar potency but shows minimal inhibition of P-glycoprotein (Pgp). CPI1 and LTC4 compete to bind to the same site of MRP1, inhibiting ATP hydrolysis and substrate transport. CPI1 can be used to study drug delivery and chemotherapy resistance in cancer.
    CPI1